Question 1

Which clinics in Seoul offer embryo genetic testing?

Accepted Answer

Seoul is a global hub for embryo genetic testing, with major institutions like Yonsei University Severance Hospital, Samsung Medical Center, and specialized clinics such as Maria Fertility Hospital and CHA Fertility Center offering advanced Preimplantation Genetic Testing (PGT-A) for aneuploidy using Next-Generation Sequencing (NGS) technology.

Clinic credentials: Yonsei University Severance Hospital is JCI-accredited and ranked highly for genetic diagnosis.
Expert surgeons: Doctors like Hong Ju at Yonseisarangmoa are adjunct professors at Yonsei University.
Advanced technology: Most top-tier Seoul centers utilize Next-Generation Sequencing to screen all 46 chromosomes.
Specialized care: Maria Fertility Hospital manages high volumes of PGT-A for up to 8 embryos.

Bookimed Expert Insight: While university hospitals offer prestige, specialized centers like Yonseisarangmoa Women’s Hospital serve over 4,500 patients annually and often provide more personalized international service. These specialized clinics frequently feature surgeons with dual academic appointments at major universities, ensuring high-level expertise without the long wait times typical of large public institutions.

Patient Consensus: Patients often recommend Maria Fertility Hospital for its efficient 10–14 day turnaround on results for 8-embryo batches. Many suggest coordinating with international departments early to manage the 10–20 million KRW budget effectively during peak seasons.

Question 2

What are the legal restrictions on embryo testing in Korea?

Accepted Answer

South Korea restricts embryo testing under the Bioethics and Biosafety Act, permitting genetic screening only for 237 specific hereditary diseases. Legal mandates strictly prohibit sex selection and wellness trait testing. Patients must provide written informed consent at registered medical institutions for any authorized genetic procedures.

Disease list: Testing is limited to 237 authorized conditions like muscular dystrophy.
Aneuploidy cap: Screening is legally capped at 8 embryos per IVF cycle.
Clinical requirements: PGT-A requires proof of 3 repeated miscarriages or IVF failures.
Storage limits: Embryos are subject to a mandatory 5-year maximum storage period.

Bookimed Expert Insight: Clinics in Seoul, such as Yonseisarangmoa Women Disease Hospital, must strictly follow the 8-embryo limit. Ministry fines for exceeding this cap are severe. Expert surgeons like Dr. Hong Jung Lee maintain high standards by focusing on medical necessity. This ensures full compliance with the 2021 Bioethics Act amendments.

Patient Consensus: Patients report that the 8-embryo limit is a hard cap with no loopholes. Most recommend freezing extra embryos untested or seeking treatment in other countries for elective screening.

Question 3

Who is recommended for this type of testing?

Accepted Answer

Genetic testing for aneuploidy (PGT-A) is primarily recommended for women aged 35 and older to reduce miscarriage risks. It is also essential for patients with recurrent pregnancy loss, multiple failed IVF transfers, or severe male factor infertility to detect chromosomal imbalances before implantation.

Advanced maternal age: Recommended for women 35+ due to higher risks of chromosomal abnormalities.
Recurrent miscarriage: Essential for patients with 2 or more consecutive pregnancy losses.
Failed IVF cycles: Advised after multiple unsuccessful embryo transfers despite good embryo quality.
Male factor infertility: Suggested when abnormal sperm parameters increase the risk of mosaic embryos.

Bookimed Expert Insight: While some clinics suggest universal testing, specialized centers like Yonseisarangmoa Women Disease Hospital in Seoul focus on high-risk cases. Data shows that testing batches of up to 8 embryos is most cost-effective for patients with low egg yields. This targeted approach prevents unnecessary transfers of non-viable embryos without over-testing younger patients with high AMH levels.

Patient Consensus: Many patients emphasize that while testing is often recommended for older women, it provides critical peace of mind by identifying issues not visible during standard embryo grading. They suggest verifying your specific medical necessity to ensure you are not paying for unnecessary procedures.

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