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Kentuckiana Integrative Medicine is a specialized clinic in Jeffersonville, Indiana. It treats patients of all ages, including children. The center focuses on regenerative, functional, and integrative medicine. A signature therapy is the Stellate Ganglion Block using platelet-rich plasma. This approach uses autologous PRP instead of standard local anesthetics. It aims for lasting relief from PTSD and chronic pain. The clinic also houses the Kentuckiana Ketamine Institute.

Dr. Rafael F. Cruz founded the practice in 2014. He has over 30 years of experience in regenerative medicine. Dr. Cruz has given ketamine for over 25 years. His institute was among the first in the region to offer it. The team reports zero serious adverse events in its ketamine program. Treatments target resistant depression, bipolar disorder, and chronic pain. Many patients improve within two weeks.

Dr. Cruz is certified in IV Chelation and Plaquex therapies. He is a member of the American Academy of Alternative Medicine. The clinic also offers EDTA-based chelation and ultrasound-guided injections. Patients travel to Louisville for these specialized regenerative protocols.