Pediatric Allogeneic Bone Marrow Transplant for Leukemia (ALL, AML, CML) at Sheba Hospital- JCI accredited and Top-10 Hospitals 2026 by Newsweek
Apa yang termasuk di paket ini
Prosedur Medis
- Hitung darah lengkap
- Analisis darah biokimia
- Konsultasi dengan ahli hematologi
- Analisis darah lanjutan
- Biopsi sumsum tulang
- Konsultasi dengan onkohematolog
- Diagnosis komprehensif Leukemia
- Studi sitogenetik dari sumsum tulang
- Transplantasi sumsum tulang
- 3 kali makan per hari oleh ahli gizi
- layanan perawat 24 jam
- Elektrokardiogram (EKG)
- Tes darah
- Rontgen dada
- Tes Anti-HIV
- Tes Anti-HBC
- Uji Anti-HCVAb
- Ekokardiografi
- Hitung darah lengkap (CBC)
- Tes darah biokimia
- PET/CT
- Konsultasi dengan ahli imunologi
- Konsultasi dengan ahli jantung
- Konsultasi dengan dokter hematologi pediatrik
- Konsultasi dengan dokter anak
- Konsultasi dengan onkohematologis
- MRI Kepala
- Biopsi
- Hitung darah lengkap dengan penanda kanker dan proteinogram
Durasi
- 30 hari di rumah sakit
Akomodasi
Rawat Inap
Transportasi
Transfer bandara-klinik-bandara
Informasi tambahan
Pediatric Allogeneic Bone Marrow Transplant for Leukemia (ALL, AML, CML)
Sheba Medical Center – Personalized, Advanced Care for Children
JCI-Accredited | Ranked Among the World’s Top 10 Hospitals by Newsweek 2026
At Sheba Medical Center, we understand that a diagnosis of leukemia in a child changes everything for a family. Our Pediatric Bone Marrow Transplant (BMT) program is designed to provide not only world-class medical care, but also reassurance, compassion, and hope at every step.
As one of the world’s leading pediatric transplant centers, Sheba combines decades of experience with cutting-edge therapies to perform allogeneic bone marrow transplantation, a transplant using healthy stem cells from a donor, for children with acute lymphoblastic leukemia (ALL), acute myeloid leukemia (AML), and chronic myeloid leukemia (CML).
For children with high-risk, relapsed, or treatment-resistant leukemia, allogeneic transplantation often offers the strongest chance for long-term cure.
When is an Allogeneic Bone Marrow Transplant Needed?
For many children, leukemia can be successfully treated with chemotherapy. However, in certain situations - such as relapse, resistance to treatment, or aggressive disease, an allogeneic bone marrow transplant becomes the most effective treatment option.
In an allogeneic transplant, the child receives healthy stem cells from a donor. These cells rebuild the bone marrow and create a new immune system capable of recognizing and fighting leukemia cells.
This approach is commonly recommended for:
High-risk ALL or AML
Relapsed leukemia
Leukemia that does not respond fully to standard therapy
Selected cases of CML and other complex hematologic conditions
A Personalized Approach to Every Child
No two children are the same, and neither are their treatments.
At Sheba, every child is evaluated by a multidisciplinary team of pediatric hemato-oncology and transplant specialists who carefully determine the optimal treatment strategy, timing, conditioning regimen, and donor source.
Whenever possible, a matched sibling donor is preferred. If a sibling match is not available, Sheba actively secures the best possible alternative donor using advanced matching technologies and international donor registries.
Donor options include:
Matched unrelated donors through global donor programs
Haploidentical (partial-match) family donors, often parents
Cord blood transplantation
With advanced HLA and molecular laboratories on-site, Sheba performs highly precise donor matching to maximize safety and transplant success.
Advanced Transplant Techniques
Sheba Medical Center is recognized internationally for utilizing some of the most advanced transplant technologies available today, including:
T-cell depletion and CD34+ selection to reduce complications and improve transplant outcomes
Integration of CAR-T cell therapy prior to transplant in selected high-risk leukemia cases
Access to innovative clinical trials and advanced cellular therapies
Personalized conditioning and supportive care protocols tailored for children
These advanced approaches allow Sheba to safely treat even highly complex or previously difficult-to-treat cases.
World-Class Outcomes
Sheba’s Pediatric BMT program consistently achieves outcomes aligned with leading international transplant centers:
ALL & AML (first or second remission): approximately 75–85% success rates
Improved outcomes in relapsed leukemia through integration of advanced cellular therapies
Strong long-term survival and quality of life for pediatric patients
Our continuous research, innovation, and clinical expertise help provide children with the best possible opportunity for cure and recovery.
Precision, Safety, and Specialized Pediatric Care
Children undergoing transplantation are cared for in dedicated pediatric transplant units designed specifically for safety, comfort, and healing.
Care includes:
Highly protected, child-friendly environments
Advanced infection prevention systems
Continuous monitoring by experienced pediatric transplant specialists
Comprehensive supportive care throughout every phase of treatment and recovery
Every aspect of care is adapted to support children physically, emotionally, and developmentally.
Care Beyond Treatment
A bone marrow transplant is more than a medical procedure - it is a journey for the entire family.
At Sheba, families receive continuous guidance, emotional support, and clear communication throughout every stage of care. Our multidisciplinary team includes physicians, nurses, psychologists, social workers, rehabilitation specialists, and international patient coordinators.
From diagnosis through long-term follow-up, we remain closely involved, helping each child not only overcome leukemia, but return to a healthy and fulfilling life.
Why Families Choose Sheba
Leading pediatric transplant center with global recognition
Expertise in complex and high-risk leukemia cases
Advanced allogeneic transplantation capabilities
Ability to secure suitable donors—even without a family match
Integration of CAR-T and advanced cellular therapies
Multidisciplinary, patient-centered pediatric care
Dedicated international patient services for a smooth experience
A Message of Hope
At Sheba Medical Center, we believe every child deserves access to the most advanced treatments available, delivered with compassion, precision, and unwavering commitment.
For children facing leukemia, allogeneic bone marrow transplantation at Sheba is more than a treatment option - it is a pathway toward healing, recovery, and a brighter future.
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Dokter
Prof. Amos Toren, MD, PhD, MHA, is a pediatric hemato-oncologist and BMT specialist. He served as Director of Pediatric Hemato-Oncology and BMT at Sheba Medical Center.
He is board certified in Pediatrics, Pediatric Hemato-Oncology, and Bone Marrow Transplantation. He holds a PhD in Human Genetics. He was Head of the Hematology Division at Tel Aviv University for two terms. He is a member of ASH, COG, ESPHI, EBMT, and CIBMTR. He also serves on the Ministry of Health Cord Blood Committee.
He led one of Israel’s most advanced pediatric oncology and BMT programs. The program treated children and young adults. His focus includes leukemia and lymphoma, immunodeficiencies, and rare cancers. He specializes in BMT and CAR T-cell therapy.
His translational research covers CAR T cells, cytokine-induced killer cells, pediatric brain tumors, and targeted therapies. He has worked with St. Anna, the NIH, and St. Jude. His publications include studies on pediatric SCT prophylaxis and PARP resistance.
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Tentang klinik
Sheba Medical Center adalah salah satu rumah sakit terbaik di Israel dan di dunia. Majalah Newsweek International menempatkan Rumah Sakit Sheba di 10 besar rumah sakit dunia pada tahun 2020. Rumah sakit ini memiliki 1.990 spesialisasi dan lebih dari 1.500.000 pasien dari seluruh dunia mengunjungi Rumah Sakit Sheba untuk pengobatan setiap tahun.
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