Sheba Pediatric CAR-T Program for Non-Hodgkin Lymphomas (DLBCL, FL, MCL) at JCI accreditated and Top-10 Hospitals 2025 by Newsweek Hospital
Apa yang termasuk di paket ini
Prosedur Medis
- Terapi sel T CAR
- 3 kali makan per hari oleh ahli gizi
- layanan perawat 24 jam
- Elektrokardiogram (EKG)
- Tes darah
- Rontgen dada
- Tes Anti-HIV
- Tes Anti-HBC
- Uji Anti-HCVAb
- Ekokardiografi
- Tes darah biokimia
- Konsultasi dengan ahli onkologi
- Konsultasi dengan ahli hematologi
- Konsultasi dengan ahli imunologi
- Konsultasi dengan ahli jantung
- Konsultasi dengan dokter hematologi pediatrik
- Konsultasi dengan dokter anak
- Konsultasi dengan onkohematologis
- MRI Kepala
- Biopsi
Durasi
- 21 hari di rumah sakit
Akomodasi
Rawat Inap
Transportasi
Transfer bandara-klinik-bandara
Informasi tambahan
Sheba Pediatric CAR-T Program for Non-Hodgkin Lymphomas (DLBCL, FL, MCL)
At Sheba Medical Center, children and young patients with Non-Hodgkin lymphomas have access to one of the most advanced and trusted CAR-T therapy programs in the world. The program focuses on treating diffuse large B-cell lymphoma (DLBCL), follicular lymphoma (FL), and mantle cell lymphoma (MCL), especially in relapsed or treatment-resistant cases using highly personalized immunotherapy.
A Personalized Treatment Designed for Each Child
CAR-T therapy uses the patient’s own immune system to identify and destroy cancer cells. This approach offers new hope for children and young patients when standard therapies are no longer effective.
At Sheba, the entire CAR-T process is performed on-site, ensuring speed, precision, and optimal cell quality:
Apheresis – collection of the patient’s T-cells
Cell Engineering – genetic modification at Sheba’s Advanced Biotherapy Center
Infusion – reintroduction of modified cells to target lymphoma
Because no steps are outsourced, treatment can begin quickly and is typically completed within ~10 days. CAR-T functions as a “living therapy,” continuing to work in the body over time and offering the potential for long-term remission.
Expert Pediatric Leadership and Care
The pediatric CAR-T program is led by Prof. Amos Toren, one of the most experienced specialists in pediatric hemato-oncology and cellular therapies, with decades of experience and over 1,500 bone marrow transplants performed.
The program includes:
Dedicated pediatric CAR-T units with 24/7 expert monitoring
A multidisciplinary team of hemato-oncologists, immunologists, and pediatric specialists
A supportive, family-centered environment designed for children
Full international patient support, including travel and care coordination
Proven Outcomes and Global Expertise
Sheba is a global leader in pediatric CAR-T therapy, with strong clinical outcomes:
~90% remission in pediatric patients
~80% in young adults (up to 23 years)
~70% in adults
The program is highly experienced in treating complex and high-risk lymphoma cases, offering advanced options when other treatments have been exhausted.
Comprehensive Evaluation and Support
Each child undergoes a thorough diagnostic evaluation, including:
advanced imaging, bone marrow testing, genetic and molecular profiling, and full cardiac and pulmonary assessment.
Care is provided in English, Russian, and Arabic, ensuring families feel supported and informed at every stage.
A Trusted Place for Advanced Pediatric Cancer Care
By combining cutting-edge science, rapid access to treatment, and compassionate pediatric care, Sheba provides one of the most trusted environments for treating Non-Hodgkin lymphomas with CAR-T therapy focused on achieving remission and helping children return to a healthy, active life.
Bantuan Bookimed 24/7
- Koordinator medis pribadi
- Pengaturan perjalanan medis — pemesanan tiket pesawat dan kamar hotel dengan harga mitra khusus
- Pendampingan pasien selama perjalanan medis
Harga program
Apa yang TIDAK termasuk di paket ini
Dokter
Prof. Amos Toren, MD, PhD, MHA, is a pediatric hemato-oncologist and BMT specialist. He served as Director of Pediatric Hemato-Oncology and BMT at Sheba Medical Center.
He is board certified in Pediatrics, Pediatric Hemato-Oncology, and Bone Marrow Transplantation. He holds a PhD in Human Genetics. He was Head of the Hematology Division at Tel Aviv University for two terms. He is a member of ASH, COG, ESPHI, EBMT, and CIBMTR. He also serves on the Ministry of Health Cord Blood Committee.
He led one of Israel’s most advanced pediatric oncology and BMT programs. The program treated children and young adults. His focus includes leukemia and lymphoma, immunodeficiencies, and rare cancers. He specializes in BMT and CAR T-cell therapy.
His translational research covers CAR T cells, cytokine-induced killer cells, pediatric brain tumors, and targeted therapies. He has worked with St. Anna, the NIH, and St. Jude. His publications include studies on pediatric SCT prophylaxis and PARP resistance.
Bagaimana pelayanan kami?
Tentang klinik
Terapi sel T CAR di Sheba Medical Center di Tel Aviv, Israel dapat memakan biaya sekitar $63.100 untuk program lengkap. Rumah sakit ini menempati peringkat 10 besar dunia dan menawarkan perawatan canggih ini di bawah pimpinan Prof. Arnon Nagler, seorang spesialis transplantasi sumsum tulang terkemuka.
Tentang Perawatan
Terapi sel T CAR adalah pendekatan inovatif untuk leukemia, limfoma, dan multipel mieloma. Prosedur ini melibatkan pengambilan sel T pasien, memodifikasinya secara genetik di laboratorium, dan memasukkannya kembali setelah kemoterapi. Proses ini memerlukan rawat inap selama 21 hari dengan kemungkinan perawatan di ICU.
Apa yang Termasuk
- Penilaian komprehensif ($5.000-$10.000)
- Pengambilan sel melalui aferesis ($6.600)
- Persiapan laboratorium untuk sel yang dimodifikasi ($20.000)
- Kondisi kemoterapi ($5.000)
- Rawat inap 21 hari ($31.500)
- Penilaian pasca-perawatan ($3.000-$5.000)
Persiapan dan Pemulihan
Pasien memerlukan biopsi sumsum tulang, pemindaian PET/CT, dan tes darah sebelum perawatan. Pemantauan harian untuk sindrom pelepasan sitokin dilakukan setelah infus. Total masa tinggal yang disarankan di Israel adalah 4-6 minggu. Perlu dicatat bahwa CAR-T untuk mieloma masih bersifat eksperimental.
Sheba Medical Center merawat 1,5 juta pasien setiap tahun dan menyediakan layanan multibahasa. Deposit sebesar $50.000-$60.000 diperlukan sebelum kedatangan. Hubungi rumah sakit untuk mendiskusikan apakah terapi ini sesuai dengan kondisi Anda.
Pembayaran & Reward
Anda tidak membayar layanan kami
Anda melakukan pembayaran langsung di klinik atau ke rekening resmi mereka.
Beberapa klinik mungkin meminta deposit sebagai bagian kebijakannya.
Bayar secara bertahap dengan opsi cicilan.
Dapatkan reward dengan mereferensikan teman ke Bookimed.